{"metadata":{"accession":"A0A8C5KKG3","id":"A0A8C5KKG3_JACJA","source_organism":{"taxId":"51337","scientificName":"Jaculus jaculus","fullName":"Jaculus jaculus (Lesser Egyptian jerboa)"},"name":"Ubiquitin-associated domain-containing protein 1","description":["Non-catalytic component of the KPC complex, a E3 ubiquitin-protein ligase complex that mediates polyubiquitination of target proteins, such as CDKN1B and NFKB1. The KPC complex catalyzes polyubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. The KPC complex also acts as a key regulator of the NF-kappa-B signaling by promoting maturation of the NFKB1 component of NF-kappa-B by catalyzing ubiquitination of the NFKB1 p105 precursor. Within the KPC complex, UBAC1 acts as an adapter that promotes the transfer of target proteins that have been polyubiquitinated by RNF123/KPC1 to the 26S proteasome"],"length":404,"sequence":"MFVQEEKIFAGKVLRLHICAADGTEWLEETTEDTSVEKLKERCLKHCAHGNLEDPKSVTHHKLIHAASERVLSDTKTILDENIQDQDVLLLIKKRAPSPLPKMAEVSAEEKKKQEQKAPDKDAILRATANLPACSTDRAAVQTTMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPESRASKALRLNHMSVPQAMEWLIEHAEDPTIDTPLPGQVPPRAGAATDAPEAAVGTSAGEEEARDELTEIFKKIRRKREFRADARAVVSLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDQGIDPNSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT","proteome":"UP000694385","gene":"Ubac1","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"b0b37d7b238df133dbb535fbe1f9b80093cc7e77","counters":{"domain_architectures":976,"entries":22,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"pfam":2,"cathgene3d":3,"ssf":2,"cdd":3,"profile":1,"smart":2,"panther":1,"interpro":8},"proteome":1,"taxonomy":1,"similar_proteins":976}}}