{"metadata":{"accession":"A0A8C4GMI7","id":"A0A8C4GMI7_DICLA","source_organism":{"taxId":"13489","scientificName":"Dicentrarchus labrax","fullName":"Dicentrarchus labrax (European seabass)"},"name":"Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase","description":["Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group"],"length":359,"sequence":"MPKRRDILAIVLIVLPWTLLITVWHQSAIAPLLAIRKACHHLVKEIFIIPERLAVRHHRLSDDGVEGKREAGGQAQDSKEYCASDKDIVEVVRTEYVYTRPPPWSDVLPTIHIITPTYSRPVQKAELTRLANTFLHVPNLHWILVEDSQRRTPLVTRLLRETGLNYTHLNVETPRNYKLRGDTRDPRIPRGTMQRNLALRWLRETFNANSSQAGIVYFADDDNTYSLELFEEMRSTRKVSVWPVAFVGGLRYESPKVNAAGKVYGWKTVFDPHRPFAIDMAGFAINLRLILFKPQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPNVEI","proteome":"UP000694389","gene":"b3gat1a","go_terms":[{"identifier":"GO:0015018","name":"galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"d24282ce8900825ece6cc7b8dc9bd15b7338eb67","counters":{"domain_architectures":8831,"entries":7,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"cdd":1,"ssf":1,"panther":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":8831}}}