{"metadata":{"accession":"A0A8C0QW67","id":"A0A8C0QW67_CANLU","source_organism":{"taxId":"286419","scientificName":"Canis lupus dingo","fullName":"Canis lupus dingo (dingo)"},"name":"Cation-dependent mannose-6-phosphate receptor","description":["Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex"],"length":278,"sequence":"MFPFFSRWRTGLLLPLLLAVAVRESWQTEEKTCDLVGEKGRESEKELALLKRLQPLYNKSFQSTVGQGPDTYIYMFRVCREAGNRTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGMEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPETSHLSVGSILLVTFASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM","proteome":"UP000694391","gene":"M6PR","go_terms":[{"identifier":"GO:0019904","name":"protein domain specific binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006622","name":"protein targeting to lysosome","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005768","name":"endosome","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0005794","name":"Golgi apparatus","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"7b22c13e99a0731092843852326f1ca71ada32a9","counters":{"domain_architectures":2716,"entries":10,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"panther":1,"pfam":1,"prints":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":2716}}}