{"metadata":{"accession":"A0A8B8W4I6","id":"A0A8B8W4I6_BALMU","source_organism":{"taxId":"9771","scientificName":"Balaenoptera musculus","fullName":"Balaenoptera musculus (Blue whale)"},"name":"Prostaglandin E synthase 3","description":["Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation"],"length":153,"sequence":"MARQHARTLWYDRPKYVFMEFCVEDSTDVHVLIEDHRIVFSCKNADGVEFYNEIEFYAKVNCKDSQDKCSGRSITCFVRKWKEKVAWPRLTKEDIKPVWLCVDFDNWRDWEGDEEVELAQVDHYAELLEKVSTKRPPPAMDDLDALDYGCCVR","proteome":"UP000694857","gene":"PTGES3L","go_terms":[{"identifier":"GO:0051879","name":"Hsp90 protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"cb338d00b2b04faff362433fd5074de637eeb145","counters":{"domain_architectures":17059,"entries":9,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"profile":1,"cathgene3d":1,"ssf":1,"cdd":1,"pfam":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":17059}}}