{"metadata":{"accession":"A0A8B7VPP3","id":"A0A8B7VPP3_CASCN","source_organism":{"taxId":"51338","scientificName":"Castor canadensis","fullName":"Castor canadensis (American beaver)"},"name":"Dihydropyrimidinase-related protein 1","description":["Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis"],"length":572,"sequence":"MSYQGKKSIPHITSDRLLIKGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVMPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKGAADIITLARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTSQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGCINVSKGVGRLIPRKPFPEYLYQRVKIRNKVSGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG","proteome":"UP001732720","gene":"Crmp1","go_terms":[{"identifier":"GO:0016810","name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016787","name":"hydrolase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"51d6f0d2568382f7084989f0f7cdc72064d17026","counters":{"domain_architectures":188509,"entries":13,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":2,"cdd":1,"pfam":1,"panther":1,"ncbifam":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":188509}}}