{"metadata":{"accession":"A0A8B7A9F2","id":"A0A8B7A9F2_ORYAF","source_organism":{"taxId":"1230840","scientificName":"Orycteropus afer afer","fullName":"Orycteropus afer afer"},"name":"Mediator of RNA polymerase II transcription subunit 7","description":["Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors"],"length":233,"sequence":"MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHTEAGIKVQTEPMDADDSNNCTGQNEQQRENSGHRRDQIIEKDAALCVLIDEMNERP","proteome":"UP000694850","gene":"MED7","go_terms":[{"identifier":"GO:0016592","name":"mediator complex","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0003712","name":"transcription coregulator activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006357","name":"regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"3862ebab031dc62b47f591e1364047d3cde2c5af","counters":{"domain_architectures":4170,"entries":8,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"panther":1,"pfam":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":4170}}}