{"metadata":{"accession":"A0A803TIM6","id":"A0A803TIM6_ANOCA","source_organism":{"taxId":"28377","scientificName":"Anolis carolinensis","fullName":"Anolis carolinensis (Green anole)"},"name":"Pyrroline-5-carboxylate reductase 3","description":["Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate (P5C) to L-proline using NAD(P)H. Proline is synthesized from either glutamate or ornithine; both are converted to P5C, and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCR3 is exclusively linked to the biosynthesis of proline from ornithine"],"length":306,"sequence":"MLSSMWAINIVAGHPSVLPSGIYPPGRTRSTLPSSSEAKSPKDNFGRYHGFSHRKLLRSQAEQLGAHHPGGQLRLFRSQNHVESQSQTSQDAASHLRSPGMGSTSYARSTAQYPKTKYWRPDGDVKAVNIFASAPSNRNLEKFQRLPAGTKVIRIIPNLPCVVQSGAIILSRGSCVGEKEVDLLKKLLSPSGLCEEAPESYIDIHTGLSGSGVAYVYMFAEALAEGAVKMGMPGPLANKIAAQTLLGAAKMMLETGEHPAALRSAVCTPGGTTIHALHELEKGGLRATVMNAVEAATNRAREMGKR","proteome":"UP000001646","gene":"PYCR3","go_terms":[{"identifier":"GO:0004735","name":"pyrroline-5-carboxylate reductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0055129","name":"L-proline biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"787ab5f47323e68e41334cd16bb6ecb1753ff295","counters":{"domain_architectures":1545,"entries":11,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":1,"pfam":1,"hamap":1,"panther":1,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":1545}}}