{"metadata":{"accession":"A0A7N4UXT8","id":"A0A7N4UXT8_SARHA","source_organism":{"taxId":"9305","scientificName":"Sarcophilus harrisii","fullName":"Sarcophilus harrisii (Tasmanian devil)"},"name":"Gamma-secretase subunit APH-1","description":["Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors"],"length":247,"sequence":"MGAAVFFGCTFVAFGPAFSLFLVTVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVTDQSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYVSGLSFGIISGVFSVINILADALGPGVVGIHGDSPFYFLTSAFLTAALILLHTFWGIVFFDACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTLSMGIWAFITAGGSLRSIQRSLSCKD","proteome":"UP000007648","gene":"APH1A","go_terms":[{"identifier":"GO:0016485","name":"protein processing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0043085","name":"positive regulation of catalytic activity","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"af84851eee3b0d24abe47b86a0182c47ae0b4d6a","counters":{"domain_architectures":3284,"entries":3,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":3284}}}