{"metadata":{"accession":"A0A7M6UW30","id":"A0A7M6UW30_NASVI","source_organism":{"taxId":"7425","scientificName":"Nasonia vitripennis","fullName":"Nasonia vitripennis (Parasitic wasp)"},"name":"SOSS complex subunit A homolog","description":["Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes. The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity. The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5"],"length":411,"sequence":"MAILTEPQDASKHYRDLTLVNRDGLTVILAHLNQMVLEKYLRLNDLAKSQLLWLLREMIRTSVTNVDNLCLSLLRHAAGGDISQRNIFLIDALLDIFQENRSWLDKFPFLVASVIYTYLRLIEDHSASHLTNLRQKEITFIVSLIRERITDCLVIGRDLVRLLQNVARIPEFETLWKDLLLNPKSLNPNFTGILQLLQTRTSRRFLQSRLTPDMERKLVFLTSTVRFGNHKRYQEWFQRQYLATPESQTLRCDLIRFIVGVIHPTNELLCSDIIPRWAVIGWLFTTCTLPVAASNAKLALFYDWLFFEPDKDNIMNIEPAILVMHNSMRSHPAVTATLLDFLCRIIPNFYPTLEDKVKSGIFSSLRQILEKRVLPSLYPLFDSPKLDRELRTKIRETFKEFCLPPNADIDY","proteome":"UP000002358","gene":null,"go_terms":null,"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"de2807dd68e1a2c8e5fd507811b0c7c78176e475","counters":{"domain_architectures":950,"entries":4,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"panther":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":950}}}