{"metadata":{"accession":"A0A7K7NRH7","id":"A0A7K7NRH7_HALAL","source_organism":{"taxId":"8969","scientificName":"Haliaeetus albicilla","fullName":"Haliaeetus albicilla (White-tailed sea-eagle)"},"name":"SAM domain-containing protein SAMSN-1","description":["Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation"],"length":371,"sequence":"QTKTSSVSQGLSSLFLQRTSSFGSFDRFRHHSISKADDAAEICELETISDIGDAVQTKAANNGGSLGKKMRAISLTMKKKMGKKYIKALSEEMNEEGKDESDPGGGIHTEKVSLKASDSMESLYSLNSGQSSSSGVTSCSDGTSNRDSLRFDDEVPYSGPFCGRAKVHTDFTPSPYDTDSLKIRKGDIIDIICKTPMGIWTGMLNNKVGNFKFIYVDIILEEEAAPRKVKLHRGSKRTKPKTLQDLLDCVHLQEYASTLLLNGYETLEDLKDLQESHLIELNISNPEDRARLLSAIENLQDYDIEQQQKSEGGQEMLSLSPHHGFDKSQLNDCPRDSGCYISSENSDNGKEEIDPETLSDMVQSVTITESN","proteome":"UP000585422","gene":"Samsn1","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"4f7b16ca4535812da860b07d38f2dbf8ab41f3f1","counters":{"domain_architectures":576,"entries":20,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"pfam":2,"ssf":2,"cathgene3d":2,"profile":2,"smart":2,"cdd":2,"panther":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":576}}}