{"metadata":{"accession":"A0A7K7K715","id":"A0A7K7K715_AGEPH","source_organism":{"taxId":"39638","scientificName":"Agelaius phoeniceus","fullName":"Agelaius phoeniceus (Red-winged blackbird)"},"name":"Type-1 angiotensin II receptor","description":["Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C","Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C"],"length":359,"sequence":"MIPNYSTEETVKRIHVDCPVSGRHSYIYIMVPTVYSIIFIIGIFGNSLVVIVIYCYMKLKTVASIFLLNLALADLCFLITLPLWAAYTAMEYQWPFGNCLCKLASAGISFNLYASVFLLTCLSIDRYLAIVHPVQSRIRRTVSVARGTCVAIWLLAGVASLPVIIHRNIFFAENLNMTVCGFRYESNNTTLRVGLGLSKNLLGFLVPFLIILTSYTLIWKTLKKAYQIQKNKTRNDDIFKMIVAIVFFFFFSWIPHQVFTFLDVLIQLHVITDCKITDIVDTAMPFTICIAYFNNCLNPFFYVFFGKNFKKYFLQLIKYIPPNVSTHPSLTTKMSSLSYRPPENIRLHTKKTAGPFDTD","proteome":"UP000521525","gene":"Agtr1","go_terms":[{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004945","name":"angiotensin type II receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019229","name":"regulation of vasoconstriction","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"587fa3dbe4504dc051049f3cca904dd9ab631b87","counters":{"domain_architectures":394800,"entries":16,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":1,"smart":1,"pfam":1,"profile":1,"panther":1,"prints":3,"prosite":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":394800}}}