{"metadata":{"accession":"A0A7K6TBC6","id":"A0A7K6TBC6_CALNI","source_organism":{"taxId":"187106","scientificName":"Caloenas nicobarica","fullName":"Caloenas nicobarica (Nicobar pigeon)"},"name":"Ribonuclease H1","description":["Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II"],"length":296,"sequence":"MLRWLVAVLSHSCFVSRGHGMFYAVRSGRRIGVFRTWAECQEQVNRFPSASFKKFATETDAWAFVRAGLPGQQQPQPQPEPAEAHGPSAVRQENGSQREEPELNVLCCNACKRPYEQPANEDHIAKRVKHNEVYSAPTVSEDKFSYMGDFAVVYTDGCCSGNGRNRARAGIGVYWGPGHPLNTSERLPGRQTNQRAEIHAACKAIEQAKSQNIKKLIIYTDSKFTINGITSWVDNWKTNGWRTSSGGSVINKEDFERLDNLSKGIEIQWMHVPGHAGFQGNEEADRLAREGASKQK","proteome":"UP000546235","gene":"Rnaseh1","go_terms":[{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004523","name":"RNA-DNA hybrid ribonuclease activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000287","name":"magnesium ion binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"08f2b2fe543027b53a1b0199bdaeb1e8940527c5","counters":{"domain_architectures":5019,"entries":18,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":2,"pfam":2,"profile":1,"cdd":1,"panther":1,"pirsf":1,"interpro":8},"proteome":1,"taxonomy":1,"similar_proteins":5019}}}