{"metadata":{"accession":"A0A7K1Y5P1","id":"A0A7K1Y5P1_9SPHI","source_organism":{"taxId":"2695275","scientificName":"Hufsiella arboris","fullName":"Hufsiella arboris"},"name":"2-amino-3-ketobutyrate coenzyme A ligase","description":["Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA","Involved in de novo bacterial ceramide synthesis. Catalyzes the condensation of L-serine with palmitoyl-CoA (hexadecanoyl-CoA) to produce 3-oxosphinganine. Also capable of using alanine as substrate leading to the formation of 1-deoxysphinganine (1-deoxySa). Contributes to the levels of endogenous sphingolipids in its host"],"length":396,"sequence":"MYDTLKPVLEEELSKIKEAGLYKTERIITSPQGADITIEGGKQVINFCANNYLGLSSHPRVIEAAKKAVDSHGYGMSSVRFICGTQDQHKELEKKISEFLGTEDTILYAAAFDANGGVFEPLFNEQDAIISDELNHASIIDGVRLCKAQRYRYKHDDMADLEAKLQETQNLRHRIVVTDGAFSMDGTIAQLDKICALAEKYRALVMIDESHCSGFMGKTGRGTHEHFNVIDKIDIITGTLGKALGGASGGFTSGKKEIIDLLRQRSRPYLFSNTLAPSITGASIAVLDMLSETTELRDTLESNTKYFRDKMTEAGFDIKPGVHPIVPVMLYDAKLSQEFAARMLDEGIYVIGFYYPVVPQNKARIRVQLSAAHTREHLDKAIAAFTKVGKELGVIK","proteome":"UP000466586","gene":"kbl","go_terms":[{"identifier":"GO:0030170","name":"pyridoxal phosphate binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009058","name":"biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0008890","name":"glycine C-acetyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006567","name":"L-threonine catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016740","name":"transferase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"220d43766bfe69807874ea078bc783ea7854e968","counters":{"domain_architectures":344728,"entries":17,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":2,"cdd":1,"pfam":1,"hamap":1,"ncbifam":2,"panther":1,"prosite":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":344728}}}