{"metadata":{"accession":"A0A7J8JGI6","id":"A0A7J8JGI6_ROUAE","source_organism":{"taxId":"9407","scientificName":"Rousettus aegyptiacus","fullName":"Rousettus aegyptiacus (Egyptian fruit bat)"},"name":"Transcription cofactor HES-6","description":["Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation"],"length":113,"sequence":"MAPLLASGRLRAGREDEDRGWEARGDRKARKPLVEKKRRARINESLHELRLLLAGPEVQAKLENAEVLELTGANSYRRKRASASPLATSNACMRCTRSCPRARPSTPPSPPSS","proteome":"UP000593571","gene":"HJG63_006225","go_terms":[{"identifier":"GO:0046983","name":"protein dimerization activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"15b86a07eaabcbc71b6ebb705399c8a22c21f484","counters":{"domain_architectures":146351,"entries":8,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"profile":1,"pfam":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":146351}}}