{"metadata":{"accession":"A0A7J8FFY8","id":"A0A7J8FFY8_ROUAE","source_organism":{"taxId":"9407","scientificName":"Rousettus aegyptiacus","fullName":"Rousettus aegyptiacus (Egyptian fruit bat)"},"name":"EARP and GARP complex-interacting protein 1","description":["Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex. Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles. Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes"],"length":387,"sequence":"MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQVGEIWHISASPADRAVLATCYNHTLDGKVLTCAAVWKMPQESEPGSHESPDDAASAAHSLELLCHLDGAAHGSTACVAWEPTGDGKRVISLADNHLLLWDLQESSSQAVLAGSASLEGRGQLKFTSGRWSPHHSCTQVATASDTAIRGWDTRTMSQVYCIENAHGQLVRDVDFNPNKQYYLASCGDDCKVKFWDTRSPAAPVRTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVTLSNMVSISSEPFGHLVDDDDLSDQEERRPEEKSQEPPQDGVIATYEEHEDSVYAVEWSSADPWLFASLSYDGRLVINRVPRALKYHILL","proteome":"UP000593571","gene":"HJG63_004402","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"a9713e78da1399cb3dcf303920c9227eff3d1889","counters":{"domain_architectures":2179,"entries":15,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"pfam":2,"cathgene3d":1,"ssf":1,"smart":1,"profile":2,"panther":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":2179}}}