{"metadata":{"accession":"A0A7J7VCB5","id":"A0A7J7VCB5_PIPKU","source_organism":{"taxId":"59472","scientificName":"Pipistrellus kuhlii","fullName":"Pipistrellus kuhlii (Kuhl's pipistrelle)"},"name":"Polycomb group RING finger protein 5","description":["Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. Plays a redundant role with PCGF3 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females"],"length":256,"sequence":"MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKVDKPKVDEEGDENQDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCPQDGPLYQSYPMVLQYRPRIDFG","proteome":"UP000558488","gene":"mPipKuh1_013204","go_terms":null,"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"5be2b93f74851266da258b611f3d2a929a6fd262","counters":{"domain_architectures":7472,"entries":16,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"cdd":2,"ssf":1,"pfam":2,"profile":1,"smart":1,"panther":1,"prosite":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":7472}}}