{"metadata":{"accession":"A0A7J6CZW2","id":"A0A7J6CZW2_9TELE","source_organism":{"taxId":"369639","scientificName":"Onychostoma macrolepis","fullName":"Onychostoma macrolepis"},"name":"Prostacyclin synthase","description":["Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE)"],"length":478,"sequence":"MMWTALLLLGLAGLLLYARRMRRRNEPPLDKGIIPWLGHALEFGKDAAKFLTRMKQKHGDIFTVRAAGQYITVLLDSNCYDAVLSDVVSLDQTGYAQVLMKRIFSLNLPNHNPESEKKRAEMHFQGSALTQLCSSMQNYLQHLVTPSEMGLKVSEWKKDGLFDFCYSLLFKTGYLTVFGAEKNNSAALAEIYEEFRRFDKLLPKLARTTENKEEKQIASSAQEKLWKLLTPSRLDRKPEHQSWLGNYVQQLQDEGVDAETQRRAMLLQLWVTQGNAGPTAFWVLGYLLTHPEALRAVREEIQGGKHLRPEETQKNTPVFDSVLSETLRLTAAALITREVKQDKKICLSNGQQYQLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADGTEKKDFFKEGVRVKYPSVPWGTKDNLCPGRQFAVSAIKELVFTILTRFDLELCDKNAKLPLVDPSRYGFGILQPAGDLEIRYRIRS","proteome":"UP000579812","gene":"G5714_007284","go_terms":[{"identifier":"GO:0004497","name":"monooxygenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005506","name":"iron ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016705","name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0020037","name":"heme binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"a02e61ba6c64bb9a9c779746e03a6c43264a16fb","counters":{"domain_architectures":520850,"entries":10,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"panther":1,"pirsf":1,"prints":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":520850}}}