{"metadata":{"accession":"A0A7J6BPI7","id":"A0A7J6BPI7_9TELE","source_organism":{"taxId":"369639","scientificName":"Onychostoma macrolepis","fullName":"Onychostoma macrolepis"},"name":"Proenkephalin-B","description":["Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin","Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress","Leumorphin has a typical opioid activity and may have anti-apoptotic effect"],"length":252,"sequence":"MMEWYVLVLMLSLPTLSQADCSAQCLRCAQQISDLDSAVNRLTCTLECEGAVPSTSTLDRCEKALQELSDEFADLNPDADGERSALNAEDLQEKASNLVKRYGGFIKRIDKNKNKFYASPWKENAILKGLFAKKYGDSLSKLGERDVPSITEDDEGEDVTAENETGVYDNDVPLNEVKRYGGFLRKFGPKRSNFVDNTSPQVLQKRYGGFMRRIRPKLRWDNQKRYGGFLRRHFKISVRSDEEPSSYEDYAL","proteome":"UP000579812","gene":"G5714_022292","go_terms":[{"identifier":"GO:0007218","name":"neuropeptide signaling pathway","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"6fa08cbd40ae6cd5bb2038f6d2313e3785d0712e","counters":{"domain_architectures":2355,"entries":6,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"prints":2,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":2355}}}