{"metadata":{"accession":"A0A7F8Q507","id":"A0A7F8Q507_LEPWE","source_organism":{"taxId":"9713","scientificName":"Leptonychotes weddellii","fullName":"Leptonychotes weddellii (Weddell seal)"},"name":"ETS translocation variant 3","description":["Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity"],"length":511,"sequence":"MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVMPNYPFINIRSSGVVPQSAPPVPTASSRFHFPPLDTHSPTSAVRPGRFSAGSLTASGQESASGADRKAELPELEDGSAADWRRGVDLLSSSSRSAVGGGLGHQKRKPDIMLPLFTRPGMYPDPHSPFAVSPLPGRGGVLNVPISPALSLTPTIFSYSPSPGLSPFTSSSCFSFNPEEMKHYLHSQACSVFNYHLSPRTFPRYPGLMVPPLQCQMHPEESAQFSIKLQPPPAGRKNRERVESSEESAPVTAPAMAPVPPRIKVEPASDKDPESLRQLVREEERSHEEGTVPSRTIEEEKGTIFARPAAPVWPSVPVSSPSEEPLEVTEDSEDRPGKEPSVPEKKEDALMPPKLRLKRRWNDDPEARELSKNGKCLWSGSGPRGLATAAADA","proteome":"UP000245341","gene":"ETV3","go_terms":[{"identifier":"GO:0003700","name":"DNA-binding transcription factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0043565","name":"sequence-specific DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006357","name":"regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9be233735550f087463761b543470356402b2953","counters":{"domain_architectures":15296,"entries":13,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"smart":1,"profile":1,"panther":1,"prosite":2,"prints":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":15296}}}