{"metadata":{"accession":"A0A6S4HJX0","id":"A0A6S4HJX0_PLUXY","source_organism":{"taxId":"51655","scientificName":"Plutella xylostella","fullName":"Plutella xylostella (Diamondback moth)"},"name":"Protein hedgehog","description":["The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product. Once cleaved, the C-product has no signaling activity and diffuses from the cell"],"length":382,"sequence":"MRAAWLILVWAGAAAACGPGRGFTGRRGPRRLMPLVFGQHVPNHGENSQSSSGPPEGRITRDDERFKDLVPNYNPDIDFKDDEGTGADRLMTQRCKERLNTLAISVMNQWPGVRLRVAEGWDEDDSHLDRSLHYEGRAVDVSTSDRDHAKYGMLARLAVEAGFDWVYYESRSYIHLSVKTESSGSGAGAGCFPGGALVRTRLGPRPVELLAPGDQVLAVDATGKVVYSEVLTFLDRDPSARWRFVRVTAESGAVLTLTPSHLLLLAAPDAFRSAFAADVVPGDVVLTRGSGAVLVPSRVVAVDYVELKGVCAPLTSEGTILVDDVLASCYAVVASHGAAHGALAPLRWLAALGAARDVPRGVHWYASFLYSTAKYLLPKSYT","proteome":null,"gene":null,"go_terms":[{"identifier":"GO:0007267","name":"cell-cell signaling","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016540","name":"protein autoprocessing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016539","name":"intein-mediated protein splicing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0007275","name":"multicellular organism development","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"ida_accession":"a73b552ecc23d61627e97e1396c48fbde1a4af23","counters":{"domain_architectures":2799,"entries":20,"isoforms":0,"proteomes":0,"sets":3,"structures":0,"taxa":1,"dbEntries":{"profile":2,"cathgene3d":2,"pfam":2,"ssf":2,"smart":1,"cdd":1,"panther":1,"prints":1,"interpro":8},"proteome":0,"taxonomy":1,"similar_proteins":2799}}}