{"metadata":{"accession":"A0A6P8TG12","id":"A0A6P8TG12_GYMAC","source_organism":{"taxId":"8218","scientificName":"Gymnodraco acuticeps","fullName":"Gymnodraco acuticeps (Antarctic dragonfish)"},"name":"GMP reductase","description":["Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation"],"length":346,"sequence":"MPRVDSDIKLDFKDVLFRPKRSSLKSRSEVDLQRTFTFRNSKQTYTGIPIIAANMDTTGTFEMAQVLSKHTLFTAIHKHYSVEDWKNFAAKNPDCVEHVAASSGSGVADLERLCAILEAVPVIKYICLDVANGYSEYFVEFVKTVRERFPKHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRIKTGVGYPQLSAVIECADSAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMMGGMLAGHDQCTGEVIEKNGKKVKLFYGMSSDTAMKKYVGGVAEYRASEGRTVEVPYRGDVNNTILDVLGGLRSTCTYVGAAKLKELSRRTTFIRVTQQSSQMFLS","proteome":"UP000515161","gene":"gmpr","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003920","name":"GMP reductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009117","name":"nucleotide metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:1902560","name":"GMP reductase complex","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"a2d25702dedbe8e7de1a6960dc2307b5a08c8f60","counters":{"domain_architectures":17457,"entries":16,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"smart":1,"cdd":1,"pfam":1,"panther":1,"pirsf":1,"hamap":1,"ncbifam":2,"prosite":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":17457}}}