{"metadata":{"accession":"A0A6P6I254","id":"A0A6P6I254_PUMCO","source_organism":{"taxId":"9696","scientificName":"Puma concolor","fullName":"Puma concolor (Mountain lion)"},"name":"Rab proteins geranylgeranyltransferase component A","description":["Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane"],"length":653,"sequence":"MADSLPTEFDVIIIGTGLPESILAAACSRSGQRVLHLDSRSYYGGNWASFNFSGLLSWLKEYQQKSDVAEESTASWQGLIHETEEAITLRKTDETIQHTEVFCYANQDMDDKIQETDALQKNPSSLTSSTLTKPLDSACLSEETHSYVTSYEMPAKDIPKNDGEISLEVSGVEGTLAEEKYCGDETCRHTVSGGDTDENKPIEEDNTDQLKRKRITYSQIVKESRRFNIDLVSKLLYSQGLLIDLLIKSNVSRYAEFKNVTRILAFREGKVEQVPCSRADVFNSKELTMVEKRILMKFLTFCLDYEQHPDQYQAFMQCSFSEYLKTKKLTPNLQHFVLHSIAMTESSCTTIDGLKATKNFLQCLGRFGNTPFLFPLYGQGEIPQCFCRMCAVFGGIYCLRHKVQCLVVDKESGRCKAIIDHLGQRINAKYFIVEDSYLSEKTCSNIQYKQISRAVLITDQSILKTDSDQQISILIVPPADSGTCAVRVTELCSSTMTCMKDTYLVHLTCSSSKTAREDLESVVKKLFTPYTEAAINEEELTKPRLLWALYFNMRDSSGVSRSSYNGLPSNVYVCSGPDCGLGNEHAVKQAETLFREIFPSEEFCPPPPNPEDIIFDGDDKQPEVSGTNNIIMAKLDSSEGSKNLESPGKHLEN","proteome":"UP000515131","gene":"CHML","go_terms":[{"identifier":"GO:0006886","name":"intracellular protein transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0018344","name":"protein geranylgeranylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005968","name":"Rab-protein geranylgeranyltransferase complex","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0005092","name":"GDP-dissociation inhibitor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007264","name":"small GTPase-mediated signal transduction","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"cfce5724cfb5347ef75c1ac7d402f6eed5f49ce2","counters":{"domain_architectures":723,"entries":15,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"ssf":2,"pfam":2,"pirsf":1,"panther":1,"prints":2,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":723}}}