{"metadata":{"accession":"A0A6P6BP29","id":"A0A6P6BP29_PTEVA","source_organism":{"taxId":"132908","scientificName":"Pteropus vampyrus","fullName":"Pteropus vampyrus (Large flying fox)"},"name":"Amyloid beta precursor like protein 2","description":["May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts"],"length":659,"sequence":"MAATWTAAAAATGRLLVLLLLRLTAPAAALAGYVEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFGTKEEVLQYCQEMYPELQITNVMEANQPVSVDNWCRRNKKQCKSHIVIPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIESAMSREKEEDDEEEDDEEEEEDYDIYKRRALVPNLEFPTEADLEDFTEAAVDDDDEDEDEGEEVVEDRDYYYDAFKGDDYNEENPTEPSNDGVISEKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKTMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTSSIAETPVDVRVSSEESDEIPPFHPFHSFPSLSENEDTQPELYHPMKKGWFVRDVSFKTHHACHFPSVSEVSCSVS","proteome":"UP000515202","gene":"APLP2","go_terms":[{"identifier":"GO:0008201","name":"heparin binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0046914","name":"transition metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004867","name":"serine-type endopeptidase inhibitor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"aad333249c83e7ee97cedb727ae5ad839f05ddb6","counters":{"domain_architectures":402,"entries":35,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":4,"smart":2,"profile":3,"ssf":4,"pfam":4,"cdd":1,"panther":1,"prosite":2,"prints":2,"interpro":12},"proteome":1,"taxonomy":1,"similar_proteins":402}}}