{"metadata":{"accession":"A0A6P6BN43","id":"A0A6P6BN43_PTEVA","source_organism":{"taxId":"132908","scientificName":"Pteropus vampyrus","fullName":"Pteropus vampyrus (Large flying fox)"},"name":"Matrix metalloproteinase-19","description":["Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin"],"length":474,"sequence":"MEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPDTARAALLQAFQYWSNVTPLTFREVQAGWADIRLSFHGRQSPYCSNTFDGPGRVLAHADIPELGSVHFDEDELWTERTYRGVNLRIIAAHELGHALGLGHSRYTQALMAPVYAGYRPHFKLHPDDVAGIQALYGKKKPEMGDEEEEMELPPVLQIPTEPSPMPDPCSGELDAMMLGPRGKTYAFKGSYVWTVTDSGLGPLFQVSALWEGLPGKLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRIEPNLDAALYWPVNQKVFLFKDSGYWQWDELARTDFTHYPKPIKRLFTGVPDQPSAAMSWKDGSVYFFKGKQYWHLNRQLRVEKGYPRDIAHNWMHCHPLTPDTTPSGGDTIPSATGIEHSPTGTTLVTTSSAIDTTLNIDHLPRNTILDTIP","proteome":"UP000515202","gene":"MMP19","go_terms":[{"identifier":"GO:0008237","name":"metallopeptidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006508","name":"proteolysis","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004222","name":"metalloendopeptidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0031012","name":"extracellular matrix","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"e7aa6275a224eebbc4d522543cda4a937af6aca1","counters":{"domain_architectures":865,"entries":24,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":3,"smart":2,"pfam":2,"cdd":2,"profile":1,"panther":1,"pirsf":1,"prints":1,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":865}}}