{"metadata":{"accession":"A0A6P5D4G2","id":"A0A6P5D4G2_BOSIN","source_organism":{"taxId":"9915","scientificName":"Bos indicus","fullName":"Bos indicus (Zebu)"},"name":"Regulator of G-protein signaling 2","description":["Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein"],"length":211,"sequence":"MQSALFLAVQHECGPMDKGAGTGPKNEEKREKMKRTLLKDWKSRLSYFLQNSSSPGKPKTGKKSKQQTFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKAKKIYTDFIEKEAPKEINIDFQTKSLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT","proteome":"UP001652663","gene":"RGS2","go_terms":null,"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"3962b823cbd84ba1c9ff3d7eb9ca5befd0245855","counters":{"domain_architectures":22883,"entries":14,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":2,"smart":1,"profile":1,"cdd":1,"pfam":1,"panther":1,"prints":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":22883}}}