{"metadata":{"accession":"A0A6P3XMT8","id":"A0A6P3XMT8_DINQU","source_organism":{"taxId":"609295","scientificName":"Dinoponera quadriceps","fullName":"Dinoponera quadriceps (South American ant)"},"name":"FACT complex subunit SSRP1","description":["Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. Binds specifically to single-stranded DNA and RNA with highest affinity for nucleotides G and U. The FACT complex is required for expression of Hox genes"],"length":738,"sequence":"MDFLEYPDIVAEVKGAMTPGKLKLTDQHLIFKSQKTGKVEQISASDMEMVNYQKFIGTWGLRIFLKNGTLHRFRGFKEADQEKIAKFFSVNYKKETLEKELSLKGWNWGTAKFTGSVLSFDVGHHTAFEIPLYDVSQCNTGKNEVTLEFHQNDDAPVSLMEMRFHIPVSDSVDQDPVEAFHQQVMEKASVISVSGDAIAIFKEIYCLTPRGRYDIKIFQTFFQLHGKTFDYKIPMSAVLRLFLLPHKDNRQMYFVVSLDPPIKQGQTRYHYLVLLFKQEEETSIELPFTEKELKEKYEDKLSKELAGPTYEVLGKVMKVIINRKLTGPGHFTGHTGTPAIGCSFKAAAGYLYPLERGFIYVHKPPIHIRFEEIASVNFARGGGSTRSFDFEIELTSGVVHTFSSIEKEEYGKLFDFIMLKKLRVKNRGKSDKLNYDQDFGDSDQEDEPDAYLARVKAEAEERDGDDNQDSEEGSTDEDFNPNQDESDVAEEYDSNPNSSDSGEDSDASAASHKKEKKEKKEKKSKSAKTVSEKPRKPRKPKKEKDANKPKRPPTAFMLWLNSARESIKADNPGIAVTEIAKKGGEMWRELKDKSEWEAKAAKAKEEYAVSMKEYEASGGGKSKDKSDKKENAGPKKKKETKKDSPSKIMSGSSFKSKEYISDDGSSSSDESKKSGKKRPSDDGDSVDEKKKKKGDKRPAESTGNASKKKRDQSDDGESDAEEVESTPPSSDAESKDSD","proteome":"UP000515204","gene":"LOC106746763","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005634","name":"nucleus","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"ba24f808451bb6dba9ceb1cecfc87f54f92fa2da","counters":{"domain_architectures":1500,"entries":29,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":4,"pfam":5,"cdd":3,"ssf":2,"smart":2,"profile":1,"panther":1,"prints":1,"interpro":10},"proteome":1,"taxonomy":1,"similar_proteins":1500}}}