{"metadata":{"accession":"A0A6P3QWA3","id":"A0A6P3QWA3_PTEVA","source_organism":{"taxId":"132908","scientificName":"Pteropus vampyrus","fullName":"Pteropus vampyrus (Large flying fox)"},"name":"Peroxisomal targeting signal 1 receptor","description":["In addition to promoting peroxisomal translocation of proteins containing a PTS1 peroxisomal targeting signal, mediates peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal via its interaction with PEX7. Interaction with PEX7 only takes place when PEX7 is associated with cargo proteins containing a PTS2 peroxisomal targeting signal. PEX7 along with PTS2-containing cargo proteins are then translocated through the PEX13-PEX14 docking complex together with PEX5","Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type). Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins. PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle"],"length":603,"sequence":"MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGTPASEAVSKPLGVASEDELVAEFLQDQSVPVVSRAPQTFKMDDLLAEMQEIEQSSFRHAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTAATDRWSDEYHPEEDLQHMASDFVAKVDDPKLANSEGTSDAWVDQFTRPVNTSALDVEFERAKSAIESDVDFWDKLQAELEEMAKREAEAHPWLSEYDDLTTASYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQHDPKHMEAWQYLGTTQAENEQELLAISALRKCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVVSGEEGASGAALGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWTTLRLALSMLGQSDAYGAADARDLSTLLAMFGLPQ","proteome":"UP000515202","gene":"PEX5","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"8bbdeee22706431f1b10d42970da591ef2279d68","counters":{"domain_architectures":1656,"entries":10,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":2,"smart":1,"profile":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":1656}}}