{"metadata":{"accession":"A0A6P3QP97","id":"A0A6P3QP97_PTEVA","source_organism":{"taxId":"132908","scientificName":"Pteropus vampyrus","fullName":"Pteropus vampyrus (Large flying fox)"},"name":"Tumor necrosis factor receptor superfamily member 5","description":["Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion"],"length":270,"sequence":"MIRLPLQCLLWGFLLTAVHPEPPTECRENQYLINSQCCNLCPPGEKLVNECTETANTKCFPCSEGEFLGTWNNERHCHQHKYCDPNLGLLVQTNGTSKTDTTCMCGEGQYCTSDACERCIPHRLCPPGFEVQQIATGVSDTICKPCPVGFFSNVSSAFEKCHRWTSCESKNLVELQAGTNKTDAVCGFQDRMRALVLIPIIMGILTIVLLVPVCIRKMTKEPENEVPVETIDIDFPGPHSTAPVQETLHGCQPVTQEDGKESRISVQERQ","proteome":"UP000515202","gene":"CD40","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0038023","name":"signaling receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0042113","name":"B cell activation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0050776","name":"regulation of immune response","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0009897","name":"external side of plasma membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"06418ac249efbd3b64e7c95ff3871218a7264c30","counters":{"domain_architectures":114,"entries":13,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"smart":1,"pfam":1,"ssf":1,"cdd":1,"panther":1,"prosite":1,"prints":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":114}}}