{"metadata":{"accession":"A0A6P3QAA6","id":"A0A6P3QAA6_PTEVA","source_organism":{"taxId":"132908","scientificName":"Pteropus vampyrus","fullName":"Pteropus vampyrus (Large flying fox)"},"name":"C-X-C chemokine receptor type 2","description":["Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2"],"length":354,"sequence":"MTIFVKNAWNFSDWEMDEAFSGTPPTENYYSPCSMDTEALNKYAVVVIYALVFLLSLLGNSLVMLVVLNGRVGRSVTDVYLLNLAVADLLFALTLPIWAISKAKGWILGTPLCKIVSFLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHWVKFICLGIWVLSLILSLPPLIVREAYQPPLSNLVCYEVMGVNTTRWRMVMRVLPQTFGFLLPLLVMLFCYGFTLRTLFQAHMGQKHRAMRVIFAVVLVFLLCWLPYNLVLVADTFMRLGVIKETCERRNDIGRALDATEILGFLHSCLNPLIYAFIGQKFRHGLLKIMAIHGLVSKEFLAKDGRPSFVGSSSGNTSTTL","proteome":"UP000515202","gene":"LOC105291073","go_terms":[{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016494","name":"C-X-C chemokine receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006935","name":"chemotaxis","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"587fa3dbe4504dc051049f3cca904dd9ab631b87","counters":{"domain_architectures":394800,"entries":13,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":1,"pfam":1,"profile":1,"panther":1,"prosite":1,"prints":2,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":394800}}}