{"metadata":{"accession":"A0A6P3I6E0","id":"A0A6P3I6E0_BISBB","source_organism":{"taxId":"43346","scientificName":"Bison bison bison","fullName":"Bison bison bison (North American plains bison)"},"name":"Leupaxin","description":["Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN)"],"length":386,"sequence":"MEELDALLEELEYSTFQESDEYSKAASPPLDQHSRKESNLDETSKVPSVPDDTNPFPVQLVYTTEIQGPNVYSEIQEPKESPPASKTSAAAQLDELMAHLCELQHQVTAKADASKKPVSDSQDHKASLDSMLGSLEQDLQNLGIATVPKGHCASCQKPIAGKVIHALGQAWHPEHFVCAHCKAEIGSSPFFERSGLAYCAEDYHHLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCAHCGEVFGEEGFHEKDKKPYCRKDFLGMFAPRCGGCNRPVLENYLSAMGTVWHPECFVCGECFSGFSTGSFFELDGRPFCELHYHQRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGVFKEQKDKTYCHPCFNKLFPV","proteome":"UP000515208","gene":"LPXN","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"b34e894464458d52d0b9522a0550a5211803efc6","counters":{"domain_architectures":2926,"entries":12,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"ssf":1,"smart":1,"pfam":1,"cdd":2,"pirsf":1,"panther":1,"prosite":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":2926}}}