{"metadata":{"accession":"A0A6J3DIG8","id":"A0A6J3DIG8_AYTFU","source_organism":{"taxId":"219594","scientificName":"Aythya fuligula","fullName":"Aythya fuligula (Tufted duck)"},"name":"Eukaryotic translation initiation factor 2A","description":["Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner"],"length":569,"sequence":"MVNGPPAFTESTAFQRDSGKNCKAVTFSKDGSLFAWCNGEKVNIFNVTSAELLRSFDLPKVVCLEFSPKNNVLATWQAYTTAKDGTAGVPNLQLYDVKTGKCLKSFIQKKMQNWCPCWADDESICARNVNNEVHFFENNNFNTIANKLHLQKVNDFVLSPGAQPTKVAVYVPGSKGAPSFVRLYQYPNFGGPQSALANKSFFKADKVTMLWNKKATAVLVIASTEVDKTGASYYGEQTLHYIATNGESAVVQLPKNGPIYDVVWNPNSVEFCAVYGFMPAKATVFNLKCDPVFDFGTGPRNAAYYSPHGHILVLAGFGNLRGQMEVWDVKNYKLVSKPVASDSTYFAWCPDGEHIVTATCAPRLRVSNGYKIWHYTGSLLHHYEVPANEEMWQVFWQPFLDGVFPVKAVKYQAVPSELPSAEPKPAQAYRPPALRNKPVTSSKLHEDEPPQNMKPQSGSSEKPLSKTALKNQKKHEAKKAAKQEAKADSNQESTQSSASQSTPRSAVPAVTSGDPETDKKIKNLKKKLKAIEQLKEQAAAGKQLEKNQLEKIQKETALLQELEDLELGL","proteome":"UP000504639","gene":"EIF2A","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003743","name":"translation initiation factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006413","name":"translational initiation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"83d9f1af1176e6c863c6b368b96fc54671f2f148","counters":{"domain_architectures":8093,"entries":9,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"panther":1,"pirsf":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":8093}}}