{"metadata":{"accession":"A0A6J2E9F4","id":"A0A6J2E9F4_ZALCA","source_organism":{"taxId":"9704","scientificName":"Zalophus californianus","fullName":"Zalophus californianus (California sealion)"},"name":"Guanine nucleotide-binding protein-like 3-like protein","description":["Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP"],"length":575,"sequence":"MMKHRHKNKKPGKGSKGCKKPAKQNGKKAASKVASAPQFVHSNDHASREAELKKKRVEEMREKQQAAREQERHRRRTIESYCQDVLQCQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLQAEGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCTVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGVTKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCIHVQKLADPVTPVETILQRCNLEEISNYYGISGFQTTEHFLTAVAHRLGKKKKGGIYSQEQAAKAVLADWVSGKISFYTLPPATHTLPAHLSAEIIKEMTEVFDIEDTEQANEDTMECLATGEADELLGDMDPLEMEIKWLHSPMMKIADAMENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPRNNSMVDVCPVDRRPVLQRIMETDPLQQGQALASALKNKKKMQKRTDKLASKLSDSMMSVLDLSGNADDSAGD","proteome":"UP000515165","gene":"LOC113931545","go_terms":[{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"4b93c256160c3eea4f0633720a92f3a06a024d5d","counters":{"domain_architectures":70445,"entries":13,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":2,"profile":1,"cdd":1,"panther":1,"pfam":1,"prints":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":70445}}}