{"metadata":{"accession":"A0A6J2CIL1","id":"A0A6J2CIL1_ZALCA","source_organism":{"taxId":"9704","scientificName":"Zalophus californianus","fullName":"Zalophus californianus (California sealion)"},"name":"Mediator of RNA polymerase II transcription subunit 16","description":["Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors"],"length":829,"sequence":"MDLAYVCEWERWPKSTHCPSVPLACAWSCRNLIAFTTDLRNDDQDLTRMIHILDTEHPWDVHSVNSEHSEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESHVGSLVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQFYKVCVSVVSEKCRIDTEILPSLFMRCTTDLNRKDKFPAITHLKFLARDMSEQVLLCASSQTSSIVECWSLRKEGLPVNNVFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQSMAVFYSSAAPRSADEPAIKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSMGHALDVSLALRHLLFLLEYCMVTGYDWWDTLLHVQPGMVQSLVEKLHEEYTRQNAALQQVLSTRILAMKASLCKLSPCTVARVCDYHAKLFLVAVSSTLKSLLRPHFLNTPDKSPGDRLTEVCTKITDADIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLASLPNQGSPLRPGHSFLRDGTSLGTLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPTSEPDEALVDECCLLPSQLLIPSLDWLPVSDGLVSRLQPKQPLRLHFGRAPTLPTSASTLQLDGLVRAPGQPKIDHLRRLHLGAYPTEECKTCTRCGCVTMLRSPNKTTAVKQWEQRWIKNCLCGGLWRRVPLSYP","proteome":"UP000515165","gene":"MED16","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016592","name":"mediator complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"8f01aa677e8de265f6fb6cca136c46ded7e4b0f3","counters":{"domain_architectures":476,"entries":19,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":2,"smart":1,"profile":2,"pfam":4,"panther":1,"interpro":8},"proteome":1,"taxonomy":1,"similar_proteins":476}}}