{"metadata":{"accession":"A0A6J1YWW4","id":"A0A6J1YWW4_ACIJB","source_organism":{"taxId":"32536","scientificName":"Acinonyx jubatus","fullName":"Acinonyx jubatus (Cheetah)"},"name":"Vasopressin V2 receptor","description":["G-protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). AVPR2 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity"],"length":372,"sequence":"MLMASSSTSAVPRPLSRPVPPGNGSKEELSDTRDPLLAQAELALLSTVFVAVALSNGLVLSALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLILSLPQLFIFAQRDVGDGTGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPAERAGGCRGGRRTGSPSEGARVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWSAWDPEAPREGPPFVLLMLLASLNSCTNPWIYAAFSSSVSSELRSLLCWARKRAPPSPGPPEESCATGSSFLAKDTSS","proteome":"UP001652583","gene":"AVPR2","go_terms":[{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005000","name":"vasopressin receptor activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"587fa3dbe4504dc051049f3cca904dd9ab631b87","counters":{"domain_architectures":340616,"entries":14,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":1,"profile":1,"pfam":1,"panther":1,"prints":3,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":340616}}}