{"metadata":{"accession":"A0A6I9ZHB6","id":"A0A6I9ZHB6_ACIJB","source_organism":{"taxId":"32536","scientificName":"Acinonyx jubatus","fullName":"Acinonyx jubatus (Cheetah)"},"name":"Translation initiation factor eIF2B subunit delta","description":["Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed"],"length":544,"sequence":"MPTQQPAAPSTGPPKPSRTLSGSLCDLFSDADSGSRMKAELSTRPGAGGREMTQEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVPAAQCQGPTKEPAGPGSQQATAGGKVLTGRSKAELRAERRAKQEADRALKQARKGEQGGPPPRACPSTAGETLPGVKRLLEHTQVDDLTLLRRLAKKPEQQQVPTRNDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPSEELSRDLVNKLKPYFSFLTQCRPLSASMYNAIKFLNKEITGVSSSKREEEAKSELQAAIDRYVQEKIVLAAQAISRFAYEKINTGDVILVYGCSSLVSRILQEAWARGRRFRVVVVDSRPRLEGRHTLRSLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLLCERGEHVALANWQNHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ","proteome":"UP001652583","gene":"EIF2B4","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"22494587f6b739b485007c3a0a6eb4fbe55754ab","counters":{"domain_architectures":23820,"entries":7,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"panther":1,"pfam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":23820}}}