"accession"	"counters"	"description"	"gene"	"go_terms"	"id"	"ida_accession"	"in_alphafold"	"is_fragment"	"length"	"name"	"protein_evidence"	"proteome"	"sequence"	"source_database"	"source_organism"
"A0A6I9PIY1"	"{'domain_architectures': 1746, 'entries': 15, 'isoforms': 0, 'proteomes': 1, 'sets': 2, 'structures': 0, 'taxa': 1, 'dbEntries': {'cathgene3d': 2, 'ssf': 1, 'pfam': 2, 'smart': 2, 'profile': 3, 'panther': 1, 'prints': 1, 'interpro': 3}, 'proteome': 1, 'taxonomy': 1, 'similar_proteins': 1746}"	"['Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as LZTS1, PSRC1 and SUV39H1. The ECS(ASB7) complex acts as a negative regulator of H3K9me3 histone mark by mediating ubiquitination and degradation of SUV39H1: ASB7 is recruited to heterochromatin by CBX5 (HP1 alpha), where it associates with SUV39H1, promoting the ubiquitin-proteasome-mediated degradation of SUV39H1. During mitosis, ASB7 is phosphorylated and inactivated, allowing SUV39H1 activity. The ECS(ASB7) complex also plays a role in spindle dynamics and genome integrity by targeting the mitotic progression protein PSRC1 for proteasomal degradation in a cell cycle-dependent manner. Also participates in meiosis by mediating the proper attachment between kinetochores and microtubules']"	"asb7"	"[{'identifier': 'GO:0005515', 'name': 'protein binding', 'category': {'code': 'F', 'name': 'molecular_function'}}]"	"A0A6I9PIY1_9TELE"	"c3174d1c628a6c37bc6fe521adf963a06a9bd960"	True	False	338	"Ankyrin repeat and SOCS box protein 7"	3	"UP000504611"	"MTKRSPSIQLVKRMLNHHCRRNPELHEELQIQAAVAAGDVCTVRRMLEQGYSPKIRDANGWTLLHFSSAKGKERCVRVFLEHGADPTVKDFIGGFTALHYAAMHGRARIARLMLESEFRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFRAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHSANIDIQNGFLLRYAVIKGNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCAQMLYTYGADTNTRNYEGQTPVAVSVSMSGISRPCLDYLQEVTRQPRTLQDLCRIQIRHCIGLQSLKLLEDLPIAKAYYLITSSAQRTCNTSSSGH"	"unreviewed"	"{'taxId': '8208', 'scientificName': 'Notothenia coriiceps', 'fullName': 'Notothenia coriiceps (black rockcod)'}"