{"metadata":{"accession":"A0A6H0KTK7","id":"A0A6H0KTK7_9BACE","source_organism":{"taxId":"2715212","scientificName":"Bacteroides faecium","fullName":"Bacteroides faecium"},"name":"dihydrouracil dehydrogenase (NAD(+))","description":["Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT)"],"length":325,"sequence":"MTDLKTTFAGLSLRNPIIISSSGLTNSVGKNKKLAEEGAGAIVLKSLFEEQIMLEAEQLRDPAFSAEGSDYLEEYIREHKLSEYLSLIKESKKVCPIPIIASINCYSDSEWVDFAKQIEEAGADALEINILALQSDVQYAYGSFEQRHIDILRHIKKTISIPVIMKLGDNLTNPVALIDQLYANGAAAVVLFNRFYQPDINIEKLEHISGEVFSNASDLATPLRWIGIASAAVDKIDYAASGGVANAESVVKAILAGASAVEVCSAVYLNTNAFIGEATRFLSAWMARKGFNSIAQFKGKLNTKDVKGINTFERTQFLKYFGKKE","proteome":"UP000501780","gene":"BacF7301_21290","go_terms":[{"identifier":"GO:0016627","name":"oxidoreductase activity, acting on the CH-CH group of donors","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004152","name":"dihydroorotate dehydrogenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006222","name":"UMP biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"386746119d361a60cfbbc9964fada353b1100670","counters":{"domain_architectures":37617,"entries":10,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cdd":1,"pfam":1,"cathgene3d":1,"ncbifam":1,"pirsf":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":37617}}}