{"metadata":{"accession":"A0A6A0AME2","id":"A0A6A0AME2_9ACTN","source_organism":{"taxId":"2705029","scientificName":"Streptomyces pacificus","fullName":"Streptomyces pacificus"},"name":"Elongation factor 4","description":["Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner"],"length":623,"sequence":"MPATPTHVPEPSRTDPALIRNFCIIAHIDHGKSTLADRMLQLTGVVEQRQMRAQYLDRMDIERERGITIKSQAVRLPWAPTTGDEQGRTHILNMIDTPGHVDFTYEVSRSLAACEGTILLVDAAQGIEAQTLANLYLAMENDLTIVPVLNKIDLPAAQPEKFSEELANLIGCDPSDVLRVSAKTGTGVEALLDRVVREVPAPVGVKDAPARAMIFDSVYDSYRGVVTYVRVVDGQLNRRERIRMMSTGATHELLEIGTNSPEMLAADGLGVGEVGYLITGVKDVRQSKVGDTITQQSKGATEALGGYKDPKPMVFSGLYPLDGSDYPELRDALDKLQLNDAALVYEPETSAALGFGFRVGFLGLLHLDVIRERLEREFGLDLIATAPNVVYRVVMEDGTEHTVTNPSEFPEGKISDVHEPVVRATILAPSEFIGSIMELCQSRRGVMLGMDYLSEDRVEIRYTLPLAEIVFDFFDQLKSKTRGYASLDYEPTGEQDAQLVKVDILLHGDKVDAFSAITHRDQAYAYGVRLVAKLKELIPRQAFEVPVQAAIGSRVIARETIRAIRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKMVGSVEVPQEAFIAVLSSDDSAGGKARK","proteome":"UP000484988","gene":"lepA","go_terms":[{"identifier":"GO:0003924","name":"GTPase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"106585660b107be25676d3abb69e435be817ee67","counters":{"domain_architectures":24937,"entries":36,"isoforms":0,"proteomes":1,"sets":7,"structures":0,"taxa":1,"dbEntries":{"ssf":3,"profile":1,"cathgene3d":5,"pfam":4,"cdd":4,"ncbifam":2,"smart":1,"hamap":1,"panther":1,"prints":1,"prosite":1,"interpro":12},"proteome":1,"taxonomy":1,"similar_proteins":24937}}}