{"metadata":{"accession":"A0A673U7P1","id":"A0A673U7P1_SURSU","source_organism":{"taxId":"37032","scientificName":"Suricata suricatta","fullName":"Suricata suricatta (Meerkat)"},"name":"P2X purinoceptor","description":["Extracellular ATP-activated non-selective cation channel. Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization","Receptor for ATP that acts as a ligand-gated ion channel"],"length":397,"sequence":"MNCVSDFFTYETTKSVVVKSWTIGVINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVTDSQCRPERFPGGGILTGRCVKYNSVIRTCEIQGWCPTEVDTVEMPVMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTAADMKKCRFHPDKAPFCPILRVGDVVKFAGQDFAKLASTGGVLGIKIGWVCDLDRAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKLENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKAKKFEEVDETMLKVTASANTVYPSDQTTEEKQSTDSGAYSIGH","proteome":"UP000472268","gene":"P2RX3","go_terms":[{"identifier":"GO:0001614","name":"purinergic nucleotide receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004931","name":"extracellularly ATP-gated monoatomic cation channel activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0033198","name":"response to ATP","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0098655","name":"monoatomic cation transmembrane transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005886","name":"plasma membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0005216","name":"monoatomic ion channel activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006811","name":"monoatomic ion transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"075c52d56606cff53863a3b664040458a3060d59","counters":{"domain_architectures":7718,"entries":14,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ncbifam":1,"panther":1,"pirsf":1,"pfam":1,"prints":2,"prosite":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":7718}}}