{"metadata":{"accession":"A0A673T6H7","id":"A0A673T6H7_SURSU","source_organism":{"taxId":"37032","scientificName":"Suricata suricatta","fullName":"Suricata suricatta (Meerkat)"},"name":"Calnexin","description":["Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse"],"length":593,"sequence":"MEGKWLLCMLLVLGTTVVRAHEGHDDDMIDIEDDLDDVIEEVEDSKLKPDTSAPPSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKEDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDQKPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELWSMTSDIFFDNFIICGDRRVVDEWASDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQSSPVEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKPEEKQKSDAEEDGGAVSQEEEDRKPKAEEDEILNRSPRNRKPRRE","proteome":"UP000472268","gene":"CANX","go_terms":[{"identifier":"GO:0005509","name":"calcium ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051082","name":"unfolded protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006457","name":"protein folding","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005783","name":"endoplasmic reticulum","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"65a0aa0a39a120a7cd886ecd6ac268e50ee5c927","counters":{"domain_architectures":8525,"entries":14,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":2,"panther":1,"pfam":1,"prints":1,"prosite":3,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":8525}}}