{"metadata":{"accession":"A0A671XG42","id":"A0A671XG42_SPAAU","source_organism":{"taxId":"8175","scientificName":"Sparus aurata","fullName":"Sparus aurata (Gilthead sea bream)"},"name":"Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1","description":["S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1)","S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway"],"length":807,"sequence":"MVCTCVSVVLSFLDSSQNESLSDPEDHRPGFSMSSRSSFDDQDGTQTASSFTMYNSVSQKLMAKMGFREGEGLGKFGQGRKEIVEASTQRGRRGLGLTLQGFQGELNVDWRDEPENHFLLAIEKVDWFPECTTENPDSDELRDWMVLGRRKLKIEDETEFCTEDLLHTLLRCKTVFDNLEGEEMRRSRTRSNPYEMIRGGIFLNRAAMKMANIDHCFDNMFTNPKDSQGKPLTKDREGELLYFGDVCAGPGGFSEYILWKRRWHAKGFGMTLKGPCDFKLEDFYAAPSELFEPYYGEGGVDGDGDITKPENITAFRNFVLENTERKGMHFLMADGGFSVEGQENLQEILSKQLLLCQFLTALSTLRTGGHFVCKTFDLFTPFSVGLVYLLYLCFERISLFKPVTSRPANSERYIVCRGLKPGSDAVREYMFKINLKLNQLRNTDMDVTEVVPLSIIKEDTDFYQFMVNSNESLCAVQIKALAKIHAYVVDPTLSEPRQADIRKECLKLWGVPDKARVAPGSSDPKSKFYELVKNSDVESFQCKLTSLSSTTLEKLRHVLDHRCIVGGGEQIFLLALGKSQIYTWDGKMPLRWRKLENFKLELPRDTLLSVEIVQELKGEGKAQRRINAVHVMDVLILNGTDVRDKHFNQRIQMAEKFVKAVAKPSRPDMNPIRVKEVYRLEEMEKIFVRLEMKVTKSSGGVPRLSYTGRDDRHFLPTGLYIIKTANEPWTMAYSKNSKMKFFYNKTTKESTYDMPPNAAAPFHVCHSERLFWAWVDGVIVHDSQTRMDPEKLSKDEVLSFVHQYYQP","proteome":"UP000472265","gene":"CMTR1","go_terms":[{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008168","name":"methyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0032259","name":"methylation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"44346f338a4b09c79755ab2cc0a9219dbb509575","counters":{"domain_architectures":1611,"entries":21,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"smart":2,"profile":3,"cathgene3d":3,"ssf":2,"cdd":1,"panther":1,"pfam":2,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":1611}}}