{"metadata":{"accession":"A0A668S9U5","id":"A0A668S9U5_OREAU","source_organism":{"taxId":"47969","scientificName":"Oreochromis aureus","fullName":"Oreochromis aureus (Israeli tilapia)"},"name":"Fatty acyl-CoA reductase","description":["Catalyzes the reduction of fatty acyl-CoA to fatty alcohols","Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols. In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis"],"length":517,"sequence":"MVNIPEYYAGKNVLISGATGFMGKVLLEKLLRSCPEVRSVYVLVRSKAGQSPKTRISEMINSKLFEKLQQDQPDFAEKIIAVNSDLTQPELNLSKADQSILAENIDIVFHCAATVRFSEPLKDAVQLNVLATQMMLALAHRMKHLEVFIHISTAYANCNRELIEEVVYSPSVDYRKLIDTLDWMDDDLVSTLTPKLIGEHPNTYTFTKSLAEYMVQQEAGDLNIAIVRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGILRTMRASNNAVADLVPVDVVINTTLAAGWYSGSQVLNRPKSIPVYNCTTGGINPFRWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLINQYWIAVSHKAPAFLYDLYLRLIGREPRMMKTITRLHKAMMVLEYFTSHSWVWNTDNMAMLLAQMSPEDKKIFNFDVRQLHWAEYMENYCMGTKKYVLNEELSGLPAARKHLNKLRNIRYTFNTILVVFIWRIFIARSQMARNIWYFVVSLCFKFLSYFRASSTMR","proteome":"UP000472276","gene":"FAR1","go_terms":[{"identifier":"GO:0080019","name":"alcohol-forming very long-chain fatty acyl-CoA reductase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"57020ac62ff987c95f8e772cb6bd806d50025c98","counters":{"domain_architectures":11146,"entries":11,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":2,"panther":1,"pfam":2,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":11146}}}