{"metadata":{"accession":"A0A5N6MBK6","id":"A0A5N6MBK6_9ASTR","source_organism":{"taxId":"192012","scientificName":"Mikania micrantha","fullName":"Mikania micrantha (bitter vine)"},"name":"Acireductone dioxygenase","description":["Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway"],"length":419,"sequence":"MGSACKDEREEVIQAWYMDDSNEDQRLPHHKEPKEFVSLDKLTEIGVLSWRLDADNYETDEELKKIRDSRGYSYMDFCEVCPEKLPNYEEKIKSFFEEHLHTDEEIRYIVAGSGYFDVRDQNEAWIRVWLKKGGMIVLPAGIYHRFTLDTDNYIKAMRLFVGDPVWTPFNRPHDHLPARKEYVEAFVHKKGAVETTNNIEIDCATIARDIMFSDAPLHVLAVDDSNLDRKLIERLLKSFSYHVTAVDSGSKALEFLGLHDVEVQNFSSFSPNPVNLVITDYCMPGMTGFELLRKIKESKSLKDVPVVIMSSDNIPARINRCLEEGAQEFFLKPVQLSDVDKLKPYMSKNKRGTTDEEEYDKSRARYDDDDDDDDDDDDDDDDDDDDDDDDNDDDEDDDMEPSFKEKDEERRSFSKDQSC","proteome":"UP000326396","gene":"E3N88_33293","go_terms":[{"identifier":"GO:0010308","name":"acireductone dioxygenase (Ni2+-requiring) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0010309","name":"acireductone dioxygenase [iron(II)-requiring] activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000160","name":"phosphorelay signal transduction system","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019509","name":"L-methionine salvage from methylthioadenosine","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"e757ebba2457af21342490a9db9ac13be92e64ea","counters":{"domain_architectures":1,"entries":18,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"pfam":2,"ssf":2,"cdd":2,"smart":1,"profile":1,"panther":1,"hamap":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":1}}}