{"metadata":{"accession":"A0A5J5CIJ1","id":"A0A5J5CIJ1_9PERO","source_organism":{"taxId":"54343","scientificName":"Etheostoma spectabile","fullName":"Etheostoma spectabile (orangethroat darter)"},"name":"Glycine--tRNA ligase","description":["Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis"],"length":737,"sequence":"MLRSAASALLRTSTEISAFCPVSTVRFVRQSLRYPPKNRPFSTSVCLCKKKKKSLWLQLAEGQTMAGNIEEILAPLRLAVKEQGDLVRQMKQDGAPDVDVTKAVAELKARKRTLEAKDIVGTSAGYRVSRTVTNVILIYRNCHYNPKMTLLTEPRWRTPSRGDSFTTRPLPSMENNILQAWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADYMVKDVKNGECFRADHLLKAHLQKLMSDKKCTAEKKAEMEEVTTQMDNYTQQELTDLFVKYNVKSPTTGNDLTPPISFNLMFQTSIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPNEKVHPKFSSVADLDITLYSSKAQTSGQSAHIMRLGEAVEQHMDNEMAHYACDCWDAEAKTSYGWIEIVGCADRSCFDLQCHARATKVPLVAEKPLKEPISLNYALLFSLTSPHKVVNVVQFEPNKGAIGKAYKKDAKIAMEYLSVCDECFITEKEQLLNESGEFTIESEGKSFKLTKDMVSVKRFQKTLHVEEVVPNVIEPSFGIGRIMYTIFEHTFHVREGDDQRTYFSFPATVAPYKCSVLPLSQNQEFMPFVKELSEAMTKNGVSYKVDDSAGSIGRRYARTDEIGVAFGITIDFDTVNKTPHTATLRDRDSMRQIRAEVSELPVIIRDLANGGLTWAEVESKYPIFEGQETSKKDTVEE","proteome":"UP000327493","gene":"FQN60_013693","go_terms":[{"identifier":"GO:0004812","name":"aminoacyl-tRNA ligase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006418","name":"tRNA aminoacylation for protein translation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000166","name":"nucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004820","name":"glycine-tRNA ligase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006426","name":"glycyl-tRNA aminoacylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"4c2844da71f0ee31f17760661b433d63c48e6904","counters":{"domain_architectures":1618,"entries":29,"isoforms":0,"proteomes":1,"sets":5,"structures":0,"taxa":1,"dbEntries":{"profile":2,"cdd":2,"cathgene3d":5,"pfam":3,"smart":1,"ssf":3,"ncbifam":2,"panther":1,"prints":1,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":1618}}}