{"metadata":{"accession":"A0A4X1SI57","id":"A0A4X1SI57_PIG","source_organism":{"taxId":"9823","scientificName":"Sus scrofa","fullName":"Sus scrofa (Pig)"},"name":"FAS-associated death domain protein","description":["Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling"],"length":211,"sequence":"MDPFLVLLHSVSASLSSSELTELKFLCQGRVGKRKLERVQSGVDLFSVLLEQNELSPEHTALLRELLVSLRRQDLLRRLDAFEAGAAGGAAPEERDLRAAFDIICDNVGKDWRRLARQLKVSDAKIDAIEEKYPRNLTEQVRESLRVWKNSRREDAAVSHLVDALRACRLNLVADLVEEEQQARASRRESGSSDPVSLISWDEDVPGSGAS","proteome":null,"gene":"FADD","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0042981","name":"regulation of apoptotic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0007165","name":"signal transduction","category":{"code":"P","name":"biological_process"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"f9d417453a13a610dfd4db30c29f560ffa4ad87e","counters":{"domain_architectures":861,"entries":16,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"smart":2,"profile":2,"pfam":2,"cdd":1,"pirsf":1,"panther":1,"interpro":5},"proteome":0,"taxonomy":1,"similar_proteins":861}}}