{"metadata":{"accession":"A0A4W4FCB6","id":"A0A4W4FCB6_ELEEL","source_organism":{"taxId":"8005","scientificName":"Electrophorus electricus","fullName":"Electrophorus electricus (Electric eel)"},"name":"acetyl-CoA C-acetyltransferase","description":["This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism"],"length":420,"sequence":"MSSAALFTTRTQLCRQLAHKYLSRTYVARPSLNEVVVVSAARTPIGSFRGSLSTVPATKLGSIAIKGAIAQAGIPLEEVKEVYMGNVLQAREGQAPTRQALLGAGLPLSTPATTINKVCASGMKSIMLAAQSLMCGHQDVMVAGGMECMSQVPYVMAREAPAYGGVMMEDLIVKDGLTDVYNKFHMGNCAENTAKNSSISREEQDTYAISSYTRSKAAWESGVLAKEVVPVSIPQKGKPDVVVKEDEEWRKVDFSKVPKLKAVFQRENGTVTAANASTLNDGAAAVVLMTADAAKRLNVVPMARIVAFADAAVAPIDFPIAPAFAVPKVLKAASIKTEDIAMWEINEAFSVVVLANIKMLDIDASKVNINGGAVSLGHPIGMSGTRIVGHMVHNLKSGQYGLASICNGGGGASSILIQRF","proteome":"UP000314983","gene":"ACAT1","go_terms":[{"identifier":"GO:0016746","name":"acyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016747","name":"acyltransferase activity, transferring groups other than amino-acyl groups","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"22ac5442f852b2fb09958cfc4b5d4345c679ae38","counters":{"domain_architectures":119306,"entries":18,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":2,"cdd":1,"panther":1,"pirsf":1,"ncbifam":1,"prosite":3,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":119306}}}