{"metadata":{"accession":"A0A4V2V0D6","id":"A0A4V2V0D6_9FIRM","source_organism":{"taxId":"682400","scientificName":"Natranaerovirga pectinivora","fullName":"Natranaerovirga pectinivora"},"name":"Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit","description":["Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor","Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT)"],"length":502,"sequence":"MELRTLNEFSARNEMEGCLICHNAPCTKRCPHGLDPAKVIRSLRFENINGAIASAKDNAICKACDTKDCVKTCLKGKVDRPVEIPSLMTYIGNINKNKGIKKVDLGIEFCGIPCENPFFLSSSVVASNYEMVAKAFEMGWAGVAFKTIGVFVPEEVSPRFSTIRKEGNSFIGFKNIEQISDHTLEENLEYLKKLKEDYPSKIIIASILGQNEEEWTYLARRMTEVGADIIECNFSCPHMTGEGLGSDVGQNPDLVALYTAATRRGTHLPILAKMTPNIGNMEIPAIAAMDNGATGIAAINTIKSIMNIHLDDFSSEPQVDGKSSVGGYSGKTVKPIALRFINDMKKHPKLVDVPISGMGGIESWRDGAEFLALGCENLQITTSVMQYGYRIIDDLIEGLSTYVGEMGFDSVQEMVGMALPKLVQAEKLNRHSISYPKFEKTNCIGCGRCYLSCYDGGHQAIEMDEDQEKPKLLPKKCVGCHLCVVVCPVGAISPGKRVEISQ","proteome":"UP000294902","gene":"EDC18_103195","go_terms":[{"identifier":"GO:0051536","name":"iron-sulfur cluster binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016627","name":"oxidoreductase activity, acting on the CH-CH group of donors","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"d32703ce400cfa057d337b9ec3b94f2eb1205aba","counters":{"domain_architectures":104,"entries":20,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"ssf":3,"pfam":3,"cdd":1,"profile":1,"panther":1,"ncbifam":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":104}}}