{"metadata":{"accession":"A0A4P8XT15","id":"A0A4P8XT15_9FIRM","source_organism":{"taxId":"2564099","scientificName":"Ruminococcus bovis","fullName":"Ruminococcus bovis"},"name":"Histidinol dehydrogenase","description":["Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine"],"length":431,"sequence":"MRIVKLTKESKNNILEGMLKRSPNNYGSYESVVADILANIKKNGDKALFEYTKKFDKFGLNKDNIRVTEEEIKDAYSKVSEDLLTVIKKSLVNVKSYHEKQRQNSWFNSTEDGTILGQKVTPLERVGVYVPGGKAVYPSSVLMNIVPAKVAGVKEIIMTTPCNSEGEVNPAVLVAANEAGVDEVYKVGGAQAIGALAYGTDSIKKVDKIVGPGNIYVALAKKAVYGFVNIDSIAGPSEILVIADETANPRFVAADLLSQAEHDELASAILITTSEDFAKKVSAEVDKFVAVLSRKEIISKSLDNFGYILVAENMDEAIDAANEIASEHLEIQTADPFLVMTKIKNAGAIFLGSYSCESLGDYFAGPNHVLPTNGTAKFFSPLSVDDFVKKSSIIYYSQDALKGVYKDVAKFARCESLTAHENAALVRFEEE","proteome":"UP000301475","gene":"hisD","go_terms":[{"identifier":"GO:0016616","name":"oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051287","name":"NAD binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004399","name":"histidinol dehydrogenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000105","name":"L-histidine biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"74c29885d030723b3b179c70eea1bde480f9dc66","counters":{"domain_architectures":29362,"entries":15,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cdd":1,"ssf":1,"cathgene3d":2,"panther":1,"hamap":1,"pirsf":1,"pfam":1,"ncbifam":1,"prosite":1,"prints":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":29362}}}