{"metadata":{"accession":"A0A4E9ETC2","id":"A0A4E9ETC2_BRUMA","source_organism":{"taxId":"6279","scientificName":"Brugia malayi","fullName":"Brugia malayi (Filarial nematode worm)"},"name":"Protein N-terminal glutamine amidohydrolase","description":["Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position"],"length":204,"sequence":"MSNCETKDCIILSKYDCDYTPMYCEENIWKLCKKVSALDELNCCSAVFISNKNRMVPLWKQRAAAAGRDYVIWDYHVILLYSKSGLVFVYDFDTTLTFPCDAQTYWTETIRPELNLDANYHRCFRVISGSHYLQHFSSDRSHMLETNGNHKALPPPWPPIYDPGIGNNLHSFISMDSHLLENISKVYDENSFSEFINEQLRSEC","proteome":"UP000006672","gene":"Bm5251","go_terms":[{"identifier":"GO:0016811","name":"hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008418","name":"protein-N-terminal asparagine amidohydrolase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0070773","name":"protein-N-terminal glutamine amidohydrolase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"32326761a8db4a7e126cdc3080a097527e7a7d2e","counters":{"domain_architectures":2655,"entries":6,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"panther":1,"pfam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":2655}}}