{"metadata":{"accession":"A0A493STR8","id":"A0A493STR8_ANAPP","source_organism":{"taxId":"8840","scientificName":"Anas platyrhynchos platyrhynchos","fullName":"Anas platyrhynchos platyrhynchos (Northern mallard)"},"name":"Metastasis-associated protein MTA3","description":["Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6"],"length":694,"sequence":"MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISNSLIMLADKHAKEVEEESETTIEVDLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLEKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADVPDMLAEGELDDREQAKLEVKVWDPDSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKHNYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYNKPNPNQISSSNGKPAAVNGAMGASYQTQASLIGRACESCYTSQSHQWYSWGPPNMQCRLCASCWIYWKKYGGLKMPTQTDEDKMSSSQPTEESHVRTHMSRQATQGTPVRNTGSPKSAVKTRQAFFLHTTCWTKLARQVCKNTLRLRQAARRPFVPINCAAIKAEYADRHCEIAGNPLKIKSTRKPLSCIIGYLEIHPAVKPNVIRSTSSLQSPSAKRLLAPSNHSSLSILGKRNYSHHNGLDESSSHTTRTIMHAAPHITHITNGKALQASASAIKTSTIPVIKRQRQNWLDASDDGFFIATEETRKIRKKFTRWQLKRASRTPCSPIIAKTKSLMNNRQARTEPRTIMH","proteome":"UP000016666","gene":"MTA3","go_terms":[{"identifier":"GO:0003682","name":"chromatin binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0043565","name":"sequence-specific DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2aaa646c3a30e8f9199fd32ec2834af291aafe38","counters":{"domain_architectures":3682,"entries":29,"isoforms":0,"proteomes":1,"sets":6,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"cdd":3,"pfam":5,"smart":4,"profile":3,"ssf":1,"panther":1,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":3682}}}